AMG 548
MedKoo试剂AMG 548(CAS864249-60-5)
产品品牌：MedKoo
产品货号：524206
产品规格：10.0mg；25.0mg；50.0mg
产品价格：咨询
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产品介绍
产品简介：
AMG-548是一种有效的选择性p38α抑制剂。它对36种其他激酶具有1000倍的选择性，并能抑制全血lps刺激的TNFα。AMG-548已被证明对急性和慢性关节炎模型有效。
产品属性：
Chemical Formula: C29H27N5O
Exact Mass: 461.22156
Molecular Weight: 461.56
Elemental Analysis: C, 75.46; H, 5.90; N, 15.17; O, 3.47
Synonym: AMG 548; AMG-548; AMG548; UNII-PGR0H531I4;
IUPAC/Chemical Name: 4(3H)-Pyrimidinone, 2-(((2S)-2-amino-3-phenylpropyl)amino)-3-methyl-5-(2-naphthalenyl)-6-(4-pyridinyl)-InChi Key: RQVKVJIRFKVPBF-VWLOTQADSA-N
InChi Code: InChI=1S/C29H27N5O/c1-34-28(35)26(24-12-11-21-9-5-6-10-23(21)18-24)27(22-13-15-31-16-14-22)33-29(34)32-19-25(30)17-20-7-3-2-4-8-20/h2-16,18,25H,17,19,30H2,1H3,(H,32,33)/t25-/m0/s1
SMILES Code: Cn1c(=O)c(c(nc1NC[C@H](Cc2ccccc2)N)c3ccncc3)c4ccc5ccccc5c4
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
产品订购：
货号 | 产品名称 | 规格 |
524206 |
AMG 548 | 10mg 25mg 50mg |
