Description: 12-Crown-4 disrupts Aβ40 fibrils. 12-Crown-4 can enter into the hydrophobic core region and form competitive, hydrophobic interactions with key hydrophobic residues.

Name: 12-Crown-4

Chemical Formula: C₈H₁₆O₄
Exact Mass: 176.1049
Molecular Weight:176.21
Elemental Analysis: C, 54.53; H, 9.15; O, 36.32

Synonym: 12-Crown-4; 12Crown4; 12 Crown 4; 12-C-4; 12C4; 12 C 4; 12-Crown-4 ether

IUPAC/Chemical Name: 1,4,7,10-Tetraoxacyclododecane

InChi Key: XQQZRZQVBFHBHL-UHFFFAOYSA-N

InChi Code: InChI=1S/C8H16O4/c1-2-10-5-6-12-8-7-11-4-3-9-1/h1-8H2

SMILES Code: O1CCOCCOCCOCC1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001