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AMG-333
MedKoo试剂AMG-333(CAS1416799-28-4)

产品品牌:MedKoo
产品货号:555318
产品规格:25.0mg;50.0mg;100.0mg;200.0mg;500.0mg;1.0g;2.0g
产品价格:咨询
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产品介绍

MedKoo试剂AMG-333(CAS1416799-28-4)

产品简介:

AMG-333是一种有效的选择性TRPM8拮抗剂,用于治疗偏头痛。AMG-33328天的大鼠和狗临床前安全性研究中耐受性良好,并已进入1期人体临床试验。

产品属性:

Chemical Formula: C20H12F5N3O4

Exact Mass: 453.0748

Molecular Weight: 453.32

Elemental Analysis: C, 52.99; H, 2.67; F, 20.95; N, 9.27; O, 14.12

Synonym: AMG-333; AMG 333; AMG333;

IUPAC/Chemical Name: (S)-6-(((3-fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic acid

InChi Key: QEBYISWYMFIXOZ-INIZCTEOSA-N

InChi Code: InChI=1S/C20H12F5N3O4/c21-12-2-1-7-26-17(12)16(10-4-6-15(13(22)8-10)32-20(23,24)25)28-18(29)14-5-3-11(9-27-14)19(30)31/h1-9,16H,(H,28,29)(H,30,31)/t16-/m0/s1

SMILES Code: O=C(O)C1=CN=C(C(N[C@@H](C2=CC=C(OC(F)(F)F)C(F)=C2)C3=NC=CC=C3F)=O)C=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

产品订购:

货号

产品名称

规格

 

 

 

555318

 

 

 

AMG-333

25.0mg

50.0mg

100.0mg

200.0mg

500.0mg

1.0g

2.0g


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