10-DEBC hydrochloride(CAS:925681-41-0)
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产品货号：574659
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产品介绍
Description: 10-DEBC, also known as Akt Inhibitor X and CCG-206734, is a cell permeable phenoxazine derivative that suppresses insulin-like growth factor 1 (IGF-1)-stimulated phosphorylation of Akt. Inhibition of Akt phosphorylation by this compound strongly correlates to the inhibition of the downstream targets, mTOR, p70S6 kinase, and S6 ribosomal protein and to an increase in apoptosis.
Name: 10-DEBC HCl
CAS#: 925681-41-0 (HCl)
Chemical Formula: C20H26Cl2N2O
Exact Mass: 380.1422
Molecular Weight: 381.34
Elemental Analysis: C, 62.99; H, 6.87; Cl, 18.59; N, 7.35; O, 4.20
Related CAS #: 201788-90-1 (free base) 925681-41-0 (HCl)
Synonym: 10-DEBC HCl; 10-DEBC hydrochloride; Akt Inhibitor X; CCG-206734; CCG 206734; CCG206734; NCP;
IUPAC/Chemical Name: 2-chloro-N,N-diethyl-10H-phenoxazine-10-butanamine, monohydrochloride
InChi Key: SVKSJUIYYCQZEC-UHFFFAOYSA-N
InChi Code: InChI=1S/C20H25ClN2O.ClH/c1-3-22(4-2)13-7-8-14-23-17-9-5-6-10-19(17)24-20-12-11-16(21)15-18(20)23;/h5-6,9-12,15H,3-4,7-8,13-14H2,1-2H3;1H
SMILES Code: ClC1=CC2=C(C=C1)OC3=CC=CC=C3N2CCCCN(CC)CC.Cl
Appearance: A crystalline solid
Purity: >95% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
