A-1331852
MedKoo试剂A-1331852 (CAS1430844-80-6)
产品品牌：MedKoo
产品货号：406841
产品规格：5.0mg; 10.0mg; 25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; 1.0g;
产品价格：咨询
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产品介绍
产品简介：
A -1331852是一种有效的bcl - xl选择性抑制剂。BCL-XL是主要的抗凋亡存活蛋白，可能成为CML治疗的新靶点。bcl - xl选择性抑制剂有可能增强多西紫杉醇治疗实体瘤的疗效，并避免纳维托克拉克斯观察到的中性粒细胞减少症加重。A-1331852可能有潜力作为一种改进的癌症治疗药物。
产品属性：
Chemical Formula: C38H38N6O3S
Exact Mass: 658.2726
Molecular Weight: 658.82
Elemental Analysis: C, 69.28; H, 5.81; N, 12.76; O, 7.29; S, 4.87
Synonym: A-1331852; A 1331852; A1331852
IUPAC/Chemical Name: 3-(1-(((3r,5r,7r)-adamantan-1-yl)methyl)-5-methyl-1H-pyrazol-4-yl)-6-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)picolinic acid
InChi Key: QCQQONWEDCOTBV-UHFFFAOYSA-N
InChi Code: InChI=1S/C38H38N6O3S/c1-22-29(19-39-44(22)21-38-16-23-13-24(17-38)15-25(14-23)18-38)27-9-10-33(41-34(27)36(46)47)43-12-11-26-5-4-6-28(30(26)20-43)35(45)42-37-40-31-7-2-3-8-32(31)48-37/h2-10,19,23-25H,11-18,20-21H2,1H3,(H,46,47)(H,40,42,45)
SMILES Code: CC1=C(C=NN1CC23CC4CC(C2)CC(C4)C3)C5=C(N=C(C=C5)
N6CCC7=CC=CC(=C7C6)C(=O)NC8=NC9=CC=CC=C9S8)C(=O)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
产品订购：
货号 | 产品名称 | 规格 |
406841 |
A-1331852 | 5.0mg 10.0mg 25.0mg 50.0mg 100.0mg 200.0mg 500.0mg 1.0g |
