3-Bromopyruvic acid(CAS#:113-59-3)
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产品介绍
Description: Bromopyruvic acid is a hexokinase II inhibitor and an effective antitumor agent. The characteristics of 3-bromopyruvate in vitro and in vivo have been reported in the scientific literature since the 1940s. Because it is a highly reactive alkylating agent and it is inherently unstable, it had been described as a metabolic poison. Research at Johns Hopkins has suggested that 3-bromopyruvate could be used to selectively kill cancer cells, while leaving normal cells intact. Recently, the FDA accepted an IND application for the use of 3-bromopyruvate for a Phase I clinical trial in liver cancer. IMPORTANT NOTE: this product we are offering is a pure chemical solid powder, which is for research use only, not for human or therapeutic use. Buyer must be a professional and understands how to use and handle the chemical properly.
Name: 3-Bromopyruvic acid
CAS#: 113-59-3
Chemical Formula: C3H3BrO3
Exact Mass: 165.92656
Molecular Weight: 166.96
Elemental Analysis: C, 21.58; H, 1.81; Br, 47.86; O, 28.75
Synonym: 3-BrPA; 3-BP; BPV; NSC 11731; NSC-11731; NSC11731; NSC 62343; NSC62343; NSC-62343; SBB053571; BRN 1746786; Bromopyruvic acid; 3-Bromopyruvic acid, bromopyruvic acid; 3-bromo-2-oxopropanoic acid; bromopyruvate; 3-bromopyruvate; beta.-Bromopyruvic acid; bromo-2-oxopropanoic acid; 3-bromo-2-oxo-propanoic acid; c-bromoacetylformate
IUPAC/Chemical Name: 3-bromo-2-oxopropanoic acid
InChi Key: PRRZDZJYSJLDBS-UHFFFAOYSA-N
InChi Code: InChI=1S/C3H3BrO3/c4-1-2(5)3(6)7/h1H2,(H,6,7)
SMILES Code: O=C(CBr)C(O)=O
Appearance: Solid powder
Purity: >97% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >10 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
