3-Methyladenine(CAS#:5142-23-4)
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产品规格：100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g;
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产品介绍
Description: 3-Methyladenine, aslo known as NSC 66389, is an Autophagy inhibitor. 3-methyladenine enhances the sensitivity of nasopharyngeal carcinoma cells to chemotherapy and radiotherapy. 3-Methyladenine can depress drug efflux transporters via blocking the PI3K-AKT-mTOR pathway thus sensitizing MDR cancer to chemotherapy. 3-methyladenine potentiates apoptosis induced by dietary tocotrienols in breast cancer cells.
Name: 3-Methyladenine
CAS#: 5142-23-4
Chemical Formula: C6H7N5
Exact Mass: 149.0701
Molecular Weight: 149.157
Elemental Analysis: C, 48.32; H, 4.73; N, 46.95
Synonym: 3-Methyladenine, NSC 66389; NSC-66389; NSC66389.
IUPAC/Chemical Name: 3-methyl-3H-purin-6-amine
InChi Key: FSASIHFSFGAIJM-UHFFFAOYSA-N
InChi Code: InChI=1S/C6H7N5/c1-11-3-10-5(7)4-6(11)9-2-8-4/h2-3H,7H2,1H3
SMILES Code: NC(N=CN1C)=C2C1=NC=N2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
