Doxorubicin-SMCC
MedKoo试剂Doxorubicin-SMCC(CAS400647-59-8)
产品品牌:MedKoo
产品货号:406622
产品规格:1.0mg; 5.0mg; 10.0mg; 25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg
产品价格:咨询
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产品介绍
产品简介:
Doxorubicin-SMCC,也称为ADR-SMCC, dox-SMCC,是阿霉素与SMCC连接剂(丁二酰-4-(N -马来酰亚甲基)环己烷-1-羧酸酯)的衍生物。多柔比星- smcc中的马来酰亚胺在pH为6.5-7.5时可与巯基反应形成稳定的硫醚键。Doxorubicin-SMCC可用于合成阿霉素与蛋白质、酶的生物偶联物;抗体、抗原和其他生物聚合物。阿霉素- smcc常用于给药研究。
产品属性:
Chemical Formula: C39H42N2O14
Exact Mass: 762.2636
Molecular Weight: 762.76
Elemental Analysis: C, 61.41; H, 5.55; N, 3.67; O, 29.37
Synonym: Doxorubicin-SMCC; ADR-SMCC; Dox-SMCC Doxo-SMCC.
IUPAC/Chemical Name: 4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)-N-((2S,3S,4S,6R)-3-hydroxy-2-methyl-6-(((1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl)oxy)tetrahydro-2H-pyran-4-yl)cyclohexanecarboxamide
InChi Key: OTQOQHVWNBKSGU-SAJDXUNTSA-N
InChi Code: InChI=1S/C39H42N2O14/c1-17-33(46)22(40-38(51)19-8-6-18(7-9-19)15-41-26(44)10-11-27(41)45)12-28(54-17)55-24-14-39(52,25(43)16-42)13-21-30(24)37(50)32-31(35(21)48)34(47)20-4-3-5-23(53-2)29(20)36(32)49/h3-5,10-11,17-19,22,24,28,33,42,46,48,50,52H,6-9,12-16H2,1-2H3,(H,40,51)/t17-,18?,19?,22-,24-,28-,33+,39-/m0/s1
SMILES Code: C[C@@H]1O[C@@H](O[C@@H](C2)C3=C(O)C(C4=O)=C(C(C5=C4C(OC)=CC=C5)=O)C(O)=C3C[C@@]2(O)C(CO)=O)C[C@H](NC(C6CCC(CN7C(C=CC7=O)=O)CC6)=O)[C@@H]1O
Appearance: Red solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
产品订购:
货号 | 产品名称 | 规格 |
406622 |
Doxorubicin-SMCC | 1.0mg 5.0mg 10.0mg 25.0mg 50.0mg 100.0mg 200.0mg 500.0mg |